Where cutting-edge clinical research and emerging technologies converge to change the future of human health innovation.

With the headquarters of UPMC and Highmark Health, Pittsburgh is also home to two top-ranked health systems where care, research, and innovation coalesce—accelerating breakthroughs from discovery to deployment.

Two top tier research universities, University of Pittsburgh and Carnegie Mellon University, are within one square mile and embody the future where AI and biotechnology intersect to open new frontiers of discovery.

Born from Pittsburgh’s industrial roots, the region now leads the way in manufacturing and robotics—driving the next generation of precision tools and smart devices for life sciences.
Pittsburgh is the birthplace of AI and home to world-class technical and scientific talent in analytics, robotics, clinical research, and advanced manufacturing. Its diverse talent pool makes it a hotspot for cross-industry collaboration, and its affordable cost of living makes it an ideal home for startups and founders to build and thrive.
MEDICAL DEVICE MANUFACTURERS
LIFE SCIENCES PUBLICATIONS
2018 - 2023
life sciences JOBS
Built on world-class talent and leading-edge discoveries, rooted in Steel City grit.
Carnegie Mellon University and the University of Pittsburgh stand at the epicenter of AI and biotech.
Carnegie Mellon University is the birthplace of AI and has the top AI program in the nation, and a track record of producing entrepreneurs at the forefront of emerging technology.
The University of Pittsburgh is a top recipient of NIH funding, mobilizing over $1.2B a year to support R+D. The University of Pittsburgh's premiere medical school hosts nationally leading programs in multiple specialties.
Their capabilities are not just complementary, they are purposefully collaborative with joint endeavours like the Pittsburgh Super Computing Center and their joint PhD program in Computational Biology that drive the sector forward.
Pittsburgh is home to two nationally ranked integrated finance and delivery networks—Highmark Health and UPMC—offering world-class clinical expertise and vast data resources that fuel life sciences and healthcare technology innovation.
Both systems actively invest in the future, with venture portfolios and startup accelerators driving breakthroughs. UPMC Enterprises alone has committed over $1 billion in the past five years to turn bold ideas into thriving businesses and transformative medicine.
The unique ecosystem of manufacturing giants, global life sciences companies, and pioneering start-ups powers prominent industry clusters in connected medical devices, data-driven healthcare, and Next-Gen therapeutics.
The future of life sciences is unfolding here—explore below for the latest highlights, headlines, and thought leadership.
Explore upcoming events that bring our life sciences community together.
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BioBreakfast is a weekly gathering of individuals in the Pittsburgh life sciences sector from 8-10 AM every Tuesday.

The 3 Rivers Venture Fair (3RVF) is Pittsburgh's premier venture capital event, connecting high-growth startups with investors, corporate partners, and innovation leaders since 2002. This annual gathering serves as a launchpad for emerging companies in tech, life sciences, advanced manufacturing, and beyond, offering curated pitch opportunities, expert insights, and high-impact networking. Known for driving real business outcomes, past participants have secured funding, formed strategic partnerships, and accelerated growth through the Fair's signature Venture Connection program - a structured matchmaking platform that pairs founders with aligned investors.

WIB-Pittsburgh, InnovatePGH, and LifeX are excited to present this event designed to connect founders and leadership teams from early-stage life science companies with companies providing support services, tools, and partnerships to accelerate their growth. Your involvement will offer a valuable opportunity for meaningful engagement within Pittsburgh’s rapidly expanding life science ecosystem.
Looking to grow or expand in the Pittsburgh region? We can connect you to the right partners and help you troubleshoot growth barriers.
Looking to move to, stay in, or recently relocated to the Pittsburgh region? Dynamic start-ups, growth stage, and mature companies are looking for top talent. We can help you connect with the right people and bring your skills and talent to this ecosystem.
Looking to invest? From pre-seed to growth stage, to highly profitable mature companies, there are life sciences and healthcare technologies across all sub-sectors that could offer value to your portfolio.